FIRST U.S. EDITION. Library of Congress Cataloging-in-Publication Data. Ridley, Matt. Genome: the autobiography of a species in 23 chapters/Matt Ridley. Francis Collins. • The Language of Life Personalized Medicine. • The Language of God Science & Religion belief. • Matt Ridley. • Genome: The Autobiography of . home using the Human Genome. Browser. To cap this, in coveries of the genome project has been that most of the .. Matt Ridley's 'Genome'. [Fourth Estate.
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PDF Genome: The Autobiography of a Species in 23 Chapters PDF File Book Details Author: Matt Ridley Pages: Binding: Paperback. the chief architects of the human genome project, which presents the Genome: The Autobiography of a. Species in 23 Chapters. By Matt. Ridley. New York. Genome Matt Ridley Notes. Uploaded by ambiz Copyright: Download as DOCX, PDF, TXT or read online from Scribd. Flag for inappropriate content.
Ridley rightly ridicules this conclusion, and explains that human complexity has little to do with the number of genes, or even the fact that alternative splicing means that there are many more protein products than genes.
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The key factor is the subtle interplay of genes, and their promoters and enhancers, in regulatory networks: it is not only what genes you have, but how and when they are expressed.
Gene expression is affected not just by other genes but also by the environment, broadly defined to include diet and exercise, as well the social environment and the mother's womb, whose effects can have lasting consequences.
Moreover, not only is gene expression also influenced by the brain, the brain itself works in part in laying down memory via gene expression responding to external signals. Thus, nature and nurture are not opposing forces, but their effects are subtly intertwined. This conclusion is hardly new, but Ridley is able to draw on the latest science -- thanks to conversations with a large number of leading scientists -- to spell out some of the emerging details to a generalist, educated reader.
He also weaves in an intelligent discussion of their implications for our understanding of our bodies and minds, our families and human society. So far, so good. Psychology textbooks including introductory, developmental, abnormal, and even physiological texts are perfunctory on findings from genetic research.
This is no doubt driven by two historical influences in psychology; namely, the influence of behaviorism and the identity conflict of psychology as a biological versus a social science. One has only to look at the areas of study once considered the exclusive province of psychology and which have now been taken over by other disciplines.
The bulk of research into these topics now resides in other disciplines, such as genetics, neurochemistry, and pharmacology.
The readers of this publication are mainly neuroscience educators who will want to consider Nature via Nurture as an educational tool. In fields such as ours with a high density of factual materials, the instructor is up against the old dilemma of not seeing the forest for looking at the individual trees.
Nature via Nurture will allow the reader to step back and consider the big picture.
In an undergraduate reading course I am happy to have an excited round table discussion among students following each chapter. My class is made up of a mixture of psychology and biology majors, and this allows me to have one student teach a concept e.
The discussions are often spirited and allow me to emphasize critical thinking, the quality of evidence, and keeping an open mind about complex problems. Finally, if one wanted to expand a basic one credit hour reading course into a more advanced format, reading the original key papers cited by Ridley would offer a challenging complement.
Genome Matt Ridley Notes
In the reading course, I asked students to pick out the two data based studies mentioned in each chapter that they found most compelling. The topics on which there was a consensus will serve to give the reader of this review a sense of the breath of topics covered by Ridley.
A unanimous selection was the adopted-away twin studies as they pertained to mental disorders. Equally fascinating to the students was the Flynn effect which shows that average IQ scores are increasing at approximately five points each decade.
Note how the first set of findings speaks to a nature explanation is affecting mental illness, while the second implies that the environment as affecting IQ scores. Mineka demonstrated this by studying fear learning in monkeys. External events and free-willed behavior can switch on genes.
Genome: The Autobiography of a Species in 23 Chapters
Genes are not omnipotent; they are at the mercy of our behavior. Another remarkable fact is that the status of a person's job is a better predictor of the likelihood of a heart attack, than obesity or high blood pressure.
Someone in a low-grade job is four times more likely to have a heart attack than a high-grade job. The reason is that low-grade jobs lead to the lack of control over one's fate, leading to an increase in stress hormones, followed by a rise in blood pressure and heart rate.
This may explain why unemployment and welfare dependency help to make people ill. It is not understood why we and all animals have evolved in such a way that stress suppresses our immune systems. The most important lesson from the book is repeated over and over again, "Genes are not there to cause diseases. This is an excellent book, very readable, and quite engaging. The author gets into some technical detail at times, without getting too bogged down in jargon.But it does not succeed as a unifying theme for his wide-ranging tour around modern genetic discoveries and their impact on the prevailing intellectual environment.
It will help you understand what this scientific milestone means for you, for your children, and for humankind. One method of dealing with large, perennial questions is to reconceptualize them and then produce a synthesis.
It will help you understand what this scientific milestone means for you, for your children, and for humankind. In the reading course, I asked students to pick out the two data based studies mentioned in each chapter that they found most compelling.
Spelled out in a billion three-letter words using the four-letter alphabet of DNA, the genome has been edited, abridged, altered and added to as it has been handed down, generation to generation, over more than three billion years. The best books combine facts with ideas, and inspire the reader to seek more answers.
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